A French baritone trained at the Conservatoire National Supérieur de Musique de Paris after studying with Mady Mesplé, Jean-Sébastien Bou is one of the most complete French-speaking singers of his generation. His international career began in 2000 with the male title role of Debussy's Pelléas et Mélisande, which he has since reprised at the Théâtre des Champs-Élysées, the Liceu in Barcelona and the Stanislavski Theatre in Moscow. He notably sang Pelléas at Opéra-Comique for the centenary of the work's premiere in 2002.
A familiar voice on the Opéra-Comique stage, he has played the title role of Rabaud's Mârouf, savetier du Caire, Frédéric in Lakmé, Raimbaud in Le Comte Ory, the Prince of Mantua in Fantasio, Lescaut in Manon. He returned in 2025 in the roles of Coppélius, Dapertutto, Lindorf and Doctor Miracle in The Tales of Hoffmann.
His eclectic repertoire stretches from the Baroque (Les Boréades conducted by William Christie and then Marc Minkowski, Monteverdi's L'Orfeo) to contemporary creation: Marc-André Dalbavie's Charlotte Salomon at the Salzburg Festival, Thierry Escaich's Claude at the Opéra de Lyon, Escaich's Point d'Orgue at the Théâtre des Champs-Élysées, Dalbavie's The Satin Slipper at the Opéra national de Paris. A renowned interpreter of mélodie, he recorded the complete songs of Charles Bordes with François-René Duchâble.